Bioflavonoids and the Capillary

Part I (Laboratory Studies) recounts the biochemistry and some of the physiological activities of the bioflavonoids. These compounds appear to be involved in the increased venular fragility of choline and vitamin C deficiencies anld in such diverse processes as: the reproductive cycle of certain algae; the biochemical activities of ascorbic acid, hyaluronidase, histamine, and epinephrine; the breeding difficulties of sheep grazed on isoflavonecontaining feeds; and the hemorrhagic complications of dicoumarol therapy. A general section on the structure of the capillary wall by Dr. Zweifach is of particular interest.